Respiratory Research Day: Universities of Nottingham, Leicester and @NottmBRCLung, @LeicesterBRC
We want to say a huge thank you to everyone who attended the University of Nottingham & University of Leicester Joint Respiratory...
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Glenn Hearson
Dec 6, 2016
The role of G protein regulated TGFβ generation in airway smooth muscle cells in Asthma
The role of G protein regulated TGFβ generation in airway smooth muscle cells in Asthma
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Glenn Hearson
Nov 7, 2016
Role of cigarette smoke and hypoxia in the development of pulmonary hypertension
What is pulmonary hypertension? Pulmonary hypertension is raised blood pressure within the pulmonary arteries, which are the blood...
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Glenn Hearson
Nov 7, 2016
Understanding the mechanisms of idiopathic pulmonary fibrosis in order to develop new treatments
IPF is a progressive and devastating lung disorder characterised by irreversible scarring (fibrosis) of the lung. IPF affects over 8,000 peo
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Glenn Hearson
Nov 4, 2016
Gq/11 signaling maintains healthy lungs
Loss of signaling by the cytokine transforming growth factor–β (TGFβ) in mice results in emphysema-like symptoms, whereas excessive TGFβ...
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Glenn Hearson
Oct 21, 2016
Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation
Allergic disease affects 30% to 40% of the world's population, and its development is determined by the interplay between environmental...
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Glenn Hearson
Sep 11, 2016
Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelia
Airway epithelial cells in cystic fibrosis (CF) overexpress Interleukin 8 (CXCL8) through poorly defined mechanisms. CXCL8 transcription is
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Glenn Hearson
Sep 4, 2016
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive disease with poor survival rates and limited treatment options. Upregulati
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