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Glenn Hearson
Oct 21, 2016
Rachel Clifford: Epigenetics of Lung Disease
I am interested in the epigenetics of lung disease, primarily asthma. Epigenetics refers to a group of processes that control how and...
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Glenn Hearson
Sep 11, 2016
Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelia
Airway epithelial cells in cystic fibrosis (CF) overexpress Interleukin 8 (CXCL8) through poorly defined mechanisms. CXCL8 transcription is
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Glenn Hearson
Sep 4, 2016
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive disease with poor survival rates and limited treatment options. Upregulati
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Glenn Hearson
Jul 15, 2016
Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ
Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ
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Glenn Hearson
Jul 14, 2016
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury
This research was published in Laboratory Investigation: http://www.nature.com/labinvest/journal/v96/n6/full/labinvest201640a.html...
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Glenn Hearson
May 28, 2016
Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with high mortality. Active TGFβ1 is considered central to the pa
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Glenn Hearson
Jun 20, 2015
CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma
Asthma is characterized by airway inflammation and remodeling and CXCL8 is a CXC chemokine that drives steroid-resistant neutrophilic airway
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